Our client, a BioPharmaceutical Company based in the North West (Manchester) is seeking a Protein Purification Scientist to join them on a Permanent Basis.
Salary package - £30-35,000
Essential Duties and Responsibilities:
You will be responsible for the primary recovery and downstream purification of therapeutic proteins produced in yeasts (2-10 L scale), as well as the implementation and use of appropriate analytical techniques for the characterisation of these proteins.
You will also be required to perform a range of biochemical methods to monitor the production processes of recombinant proteins and to confirm the quality of products.
You will be required to participate in process validation and scale-up activities (GMP and non-GMP).
Requirements:
Proven experience in the purification and characterisation of recombinant proteins and development and validation of associated analytical methods
Qualifications:
M.Sc. or Ph. D in Biochemistry together with at least 4 years' relevant experience. Lower qualifications will be considered if the applicant can demonstrate significant practical experience.
The successful candidate will have:
"Minimum 4 years' practical experience in the field of protein purification techniques (affinity, ion exchange, hydrophobic interaction and size exclusion chromatography) and sample analysis techniques SDS-PAGE, HPLC, ELISA and western blotting).
"Familiarity with AKTA chromatography systems and Unicorn software.
"Flexibility to work on projects across all phases of product development - including assay development, assay validation and quality control testing.
General Requirements For This Position:
"Highly self-motivated, independent and flexible individuals
"Must have good interpersonal skills to work effectively as part of multidisciplinary project teams.
"To apply for this position, candidates must be eligible to live and work in the UK
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